Publicaciones

Publicaciones de estudios en los que ha colaborado SCReN

2019

Estudio 13.007-MAGIC BULLET

Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator driven, open-label, randomized, noninferiority controlled trial

José M. Cisneros, Clara María Rosso-Fernández, Cristina Roca-Oporto, Gennaro De Pascale, Silvia Jiménez-Jorge, Esteban Fernández-Hinojosa, Dimitrios K. Matthaiou, Paula Ramírez, Ramón Ortiz Díaz-Miguel, Angel Estella, Massimo Antonelli, George Dimopoulos, José Garnacho-Montero and on behalf of the Magic Bullet Working Group WP

 

Critical Care. 2019 23:383

DOI: 10.1186/s13054-019-2627-y
PMID: 31779711
Trials Registration Number: NCT01292031

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Publicación del estudio fase II previo a estudio 19.813-REVISIT

Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study

Oliver A. Cornely , Jose M. Cisneros, Julian Torre-Cisneros, Maria Jesu´s Rodriguez-Hernandez, Luis Tallon-Aguilar, Esther Calbo, Juan P. Horcajada, Christian Queckenberg, Ulrike Zettelmeyer, Dorothee Arenz, Clara M. Rosso-Fernandez, Silvia Jimenez-Jorge, Guy Turner, Susan Raber, Seamus O’Brien and Alison Luckey on behalf of the COMBACTE-CARE consortium/REJUVENATE Study Group

 

J Antimicrob Chemother. 2020 Mar 1;75(3):618-627

DOI: 10.1093/jac/dkz497
PMID: 31828337
Trials Registration Number REJUVENATE: NCT02655419

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Estudio 16.014-INMEDIATE

Inhaled methoxyflurane provides greater analgesia and faster onset of action versus standard analgesia in patients with trauma pain. InMEDIATE: a randomized controlled trial in Emergency

Borobia A, García Collado S, Carballo Cardona C, Capilla Pueyo R, Fernández Alonso C, Pérez Torres I, Corell González M, Casal Codesido JR, Arranz Betegón M, Amador Barcela L, Odiaga Andicoechea A, Fernández Testa A, Trigo Colina J, Cid Dorribo A, del Arco Galán C, Carlos Martínez Ávila J, Traseira Lugilde S, Carcas Sansuán Antonio J

 

Ann Emerg Med. 2019 Oct 14. pii: S0196-0644(19)30614-6 (Epub ahead of print)

DOI: 10.1016/j.annemergmed.2019.07.028
PMID: 31623936

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Estudio 16.027-LIVERHOPE_SAFETY

Safety of two different doses of simvastatin in combination with rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial

Pose E, Napoleone L,Amin A, Campion D, Jimenez C, Piano S, Roux O, Erhard Uschner F, de Wit K, Zaccherini G, Alessandria C, Angeli P, Bernardi P, Beuers U, Caraceni P, Durand F, P. Mookerjee R, Trebicka J, Vargas V, Andrade RJ, Carol M, Pich J, Ferrero J, Domenech G, Llopis M, Torres F, Kamath PS, Abraldes JG, Sola E, Gines P

 

Lancet Gastroenterol Hepatol. 2020 Jan;5(1):31-41

DOI: 10.1016/S2468-1253(19)30320-6
PMID: 31607677
Trials Registration Number: NCT03150459
EU Clinical Trials Register: 2016-004499-23

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Estudio 14.013-AMIKACINA

Evaluating the optimal time for amikacin administration with respect to haemodialysis using an in vitro pharmacodynamic simulation against epidemic nosocomial OXA-48 producing Klebsiella pneumoniae ST405 strains.

Carcas AJ, Sevillano D, González N, Alou L, Gómez-Gil R, Muñoz M, Llanos L, Sanchez-Villanueva RJ, Gonzalez-Parra E, Giménez MJ, Aguilar L

 

J Glob Antimicrob Resist. 2019 Dec;19:241-251

DOI: 10.1016/j.jgar.2019.05.027
PMID: 31176754

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2018

Estudio 13.011-PESAPRO

Cervical Pessary Compared With Vaginal Progesterone for Preventing Early Preterm Birth: A Randomized Controlled Trial

Cruz-Melguizo S, San-Frutos L, Martínez-Payo C, Ruiz-Antorán B, Adiego-Burgos B, Campillos-Maza JM, García-González C, Martínez-Guisasola J, Pérez-Carbajo E, Teulón-González M, Avendaño-Solá C, Pérez-Medina T

 

Obstet Gynecol. 2018 Oct;132(4):907-915

DOI: 10.1097/AOG.0000000000002884
PMID: 30204689
Trials Registration Number: NCT01643980
EU Clinical Trials Register: 2012-000241-13

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2017

Estudio 15.010-HOW LONG

Optimisation of empirical antimicrobial therapy in patients with haematological malignancies and febrile neutropenia (How Long study): an open-label, randomised, controlled phase 4 trial

Aguilar-Guisado M, Espigado I, Martín-Peña A, Gudiol C, Royo-Cebrecos C, Falantes J, Vázquez-López L, Montero MI, Rosso-Fernández C, de la Luz Martino M, Parody R, González-Campos J, Garzón-López S, Calderón-Cabrera C, Barba P, Rodríguez N, Rovira M, Montero-Mateos E, Carratalá J, Pérez-Simón JA, Cisneros JM

 

Lancet Haematol. 2017 Dec;4(12):e573-e583

DOI: 10.1016/S2352-3026(17)30211-9
PMID: 29153975
Trials Registration Number: NCT01581333

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2016

Estudio 13.015-PR196-10

Impact of preemptive fibrinogen concentrate on transfusion requirements in liver transplantation: a multicenter, randomized, double-blind, placebo-controlled trial

Sabate A, Gutierrez R, Beltran J, Mellado P, Blasi A, Acosta F, Costa M, Reyes R and Torres F

American Journal of Transplantation 2016 Aug; 16(8): 2421-9

DOI: https://doi.org/10.1111/ajt.13752
PMID: 26880105
Trial Registration Number: NCT01539057

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Estudio 13.015-PR196-10

Assessment of rotational thromboelstometry for the prediction of red cell requirements in orthotopic liver transplantation

Sabate A, Blasi A, Costa M, reyes R, Beltran J, Torres F

 

Minerva Anestesiolol 2018Apr; 84(4): 447-454

DOI: 10.23736/S0375-9393.17.12023-7
PMID: NCT01539057

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Estudio 13.005-PG ON09

Ensayo clínico aleatorizado triple ciego y multicéntrico para evaluar la eficacia en la disminución del dolor y el grado de satisfacción de una mezcla de óxido nitroso y oxígeno (N2O/O2) 50/50 como tratamiento añadidoal convencional en los pacientes atendidos por cólico nefrítico en el servicio de urgencias

Aguilar Mulet JM, Álvarez Rodríguez V, Borobia Pérez AM, Velayos Rubio R, Ochoa Mazarro MD, Arco Galán C

 

Emergencias 2016;28:305-312

PMID: 29106100

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2013

Estudio 13.009-IJP PEN

Efficacy of high doses of penicillin versus amoxicillin in the treatment of uncomplicated community acquired pneumonia in adults. A non-inferiority controlled clinical trial

Llora C, Pérez A, Carandellc E, García-Sangenís A, Rezolac J, Llorente M, Gestoso S, Bobé F, Román-Rodríguez M, Cots JM, Hernández S, Cortés J, Miravitlles M, Morros R

 

BMC Family Practice, 14: 50 (2013)

DOI: 10.1016/j.aprim.2017.08.003
PMID: 29061311
PMICID (texto completo PubMed) : PMC6836912

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Otras publicaciones SCReN

SCReN: Spanish Research Netwok; one-Year Experience

Vargas E, Calvo-Rojas G, Avendaño C, Portoles A, Galvez M, Arnau JM, Rosso C, Torres F, Gómez de la Camara A, Pavia M

Clinical Therapeutics , Volume 37 , Issue 8 , e140.

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Protocolos SCReN

2019

Estudio 18.010-NO BACT

Opportunities for antibiotic optimisation and outcome improvement in patients with negative blood cultures: study protocol for a cluster-randomised crossover trial, the NO-BACTstudy

Silvia Jiménez-Jorge, Zaira R Palacios-Baena, Clara M Rosso-Fernández, José A Girón-Ortega, Jesús Rodriguez-Baño, Pilar Retamar

 

BMJ Open. 2019 9: e030062

DOI: 10.1136/bmjopen-2019-030062
PMID: 31857298
PMICID (texto completo PubMed) : PMC6937003
Trials Registration Number: NCT03535324

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Estudio 18.008-CYTOCOR

Efficacy and safety of the combination of reduced duration prophylaxis followed by immuno-guided prophylaxis to prevent cytomegalovirus disease in lung transplant recipients (CYTOCOR STUDY): an open-label, randomised, non-inferiority clinical trial

Paez-Vega A, Cantisan S, Vaquero JM, Vidal E, Luque-Pineda A, Lobo-Acosta MÁ, Pérez AB, Alonso-Moralejo R, Iturbe D, Monforte V, Otero-Gonzalez I, Pastor A, Ussetti P, Torre-Cisneros J

 

BMJ Open. 2019 Aug 15;9(8):e030648

DOI: 10.1136/bmjopen-2019-030648
PMID: 31420397
PMICID (texto completo PubMed) : PMC6937003
Trials Registration Number: NCT03699254

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2018

Estudio 17.006-MOSCAFRAIL

Invasive Versus Conservative Strategy in Frail Patients With NSTEMI:The MOSCA-FRAIL Clinical Trial Study Design

Sanchis J, et al.

 

Rev Esp Cardiol (Engl Ed). 2019 Feb;72(2):154-159

DOI: 10.1016/j.rec.2018.02.007
PMID: 29525724
Trial Registration Number: NCT03208153

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Estudio 16.028-ORTHOUNION

A Multicentric, Open-Label, Randomized, Comparative Clinical Trial of Two Different Doses of Expanded hBM-MSCs Plus Biomaterial versus Iliac Crest Autograft, for Bone Healing in Nonunions after Long Bone Fractures: Study Protocol

Gómez-Barrena E , Padilla-Eguiluz NG, Avendaño-Solá C, et al

 

Stem Cells International Volume 2018, Article ID 6025918, 13 pages

DOI: 10.1155/2018/6025918
PMID: 29535772
PMCID (texto completo) : PMC5842679
Eudra CT: 2015-000431-32

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2017

Estudio 16.014-INMEDIATE

Phase IIIb, open label randomised clinical trial to compare pain relief between methoxyflurane and standard of care for treating patients with trauma pain in Spanish Emergency Units (InMEDIATE): Study protocol

Borobia Pérez AM, Capilla Pueyo R, Casal Codesido JR, Fernández Testa A, Martínez Ávila, JC, García Morales T, Traseira Lugilde S, Carcas Sansuán AJ, InMEDIATE Group


IBJ Clin Pharmacol 2017 1(1):e0008

DOI: 10.24217/2530-4984.17v1.00008
Trials Registration Number: NCT03256903
Eudra CT: 2017-000338

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Estudio 16.001-SIMPLIFY

Targeted simplification versus antipseudomonal broad-spectrum betalactams in patients with bloodstream infections due to Enterobacteriaceae (SIMPLIFY): a study protocol for a multicentre, open-label, phase III randomised, controlled, non-inferiority clinical trial

López-Cortés LE, Rosso-Fernández C, Núñez-Núñez M, et al

BMJ Open 2017;7:e015439

DOI: 10.1136/bmjopen-2016-015439
PMID: 28601833
PMCID: PMC5734512
Trials Registration Number: NCT02795949
Eudra CT: 2015-004219-19

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2015

Estudio 13.011-PESAPRO

Evaluation of two treatment strategies for the prevention of preterm birth in women identified as at risk by ultrasound (PESAPRO Trial): study protocol for a randomized controlled trial

Cabrera-García L, Cruz-Melguizo S, Ruiz-Antorán B, Torres F, Velasco A, Martínez-Payo C, Avendaño-Solá C; PESAPRO trial Group

Trials. 2015 Sep 25;16:427

DOI: 10.1186/s13063-015-0964-y
PMID: 26407852
PMCID: PMC4584019
Trials Registration Number: NCT01643980
Eudra CT: 2012-000241-13

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2013

Estudio 13.009-IJP PEN

Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial

Llor C, Arranz J, Morros R, García-Sangenís A, Pera H, Llobera J, Guillén-Solà M, Carandell E, Ortega J, Hernández S, Miravitlles M

BMC Family Practice 2013 Apr 17;14:50. doi: 10.1186/1471-2296-14-50

DOI: doi: 10.1186/1471-2296-14-50
PMID: 23594463
PMCID: PMC3637575
Eudra CT: 2012-003511-63

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Instrucciones

¿Cómo nombrar SCReN, ISCIII y FEDER en las publicaciones?

Deberán mencionar:

  • Ministerio de Ciencia, Innovación y Universidades (MICINN)
  • Instituto de Salud Carlos III y Plan Nacional de I+D+i
  • Plataforma de Unidades de Investigación Clínica y Ensayos Clínicos (SCReN) y nº de expediente PT13/0002/00XX, PT17/0017/00XX
  • Si está cofinanciado por Fondos FEDER o por el Fondo Social Europeo FSE